Amedzofe, located in the mountainous region of the Volta Region in Ghana, lies to the north of Ho within the newly established Ho-West District. Positioned at an altitude of 677 meters (2,221 feet) above sea level, the settlement is known for its stunning natural features, including the Ote Falls, Mount Gemi, and its favorable weather and landscapes. Amedzofe has historical significance, having played a role in the 19th-century Anglo-Ashanti Wars. It is also home to the Amedzofe Training School, founded in 1880 by German missionaries, and the oldest Evangelical Presbyterian Church in the Avatime Traditional Area, established in 1889.