Medine, located in Mali's Kayes Region, is a village with rich historical significance. It serves as the administrative center of the Hawa Dembaya commune and lies along the Sénégal River near Félou Falls. Once a strategic French military post established in 1855, it endured a notable 97-day siege in 1857. Present-day Medine features the preserved Fort de Médine, a 19th-century railway station, and a colonial-era cemetery, along with a small daily market. The fort is also listed on Mali's UNESCO World Heritage tentative list.