South Kitui National Reserve, in Kenya's Eastern Province, spans about 1,831–1,833 square kilometers and was officially gazetted in 1979. It lies north of Tsavo East National Park and forms part of the Tsavo Conservation Area, acting as a movement corridor for wildlife such as lions, elephants, giraffes and leopards between Tsavo and the reserve.
The landscape consists of acacia savannah, grasslands, thickets, along with patches of baobab and saltbush. Due to its varied terrain and relatively undeveloped infrastructure, it remains one of Kenya's less crowded reserves. Wildlife is rich: beyond the large mammals, primates are particularly noteworthy, and there are many resident and migratory bird species benefitting from the ecological diversity.